It is located directly on the River Rhine, a 5-minute drive from the center of Koblenz. All rooms at Hotel zwei&vierzig are traditionally furnished and feature Wi-Fi and a private bathroom. Vallendar railway station is just an 8-minute walk from the Alexander von Humboldt. Hotel guests are just a 3-minute drive from the A48 motorway, and a 10-minute drive from the A3 and A61 motorways. The Westerwald, Eifel and Hunsrück regions are good day trip destinations from here.